| # | Name | Origin | Meaning | Gender | |
|---|---|---|---|---|---|
| 281 | Ema | Spanish | Grandmother. | F | |
| 282 | Emerald | Spanish | The prized green emerald gemstone. | F | |
| 283 | Emesta | Spanish | Serious. | F | |
| 284 | Emilia | Spanish | Flattering. | F | |
| 285 | Emilie | Spanish | Flattering. | F | |
| 286 | Encarnacion | Spanish | Reference to the Incarnation. | F | |
| 287 | Engracia | Spanish | Graceful. | F | |
| 288 | Enrica | Spanish | Rules her household. Feminine of Henry. | F | |
| 289 | Enriqua | Spanish | Ruler. | F | |
| 290 | Enriqueta | Spanish | Ruler. | F | |
| 291 | Erendira | Spanish | Name of a princess. | F | |
| 292 | Erendiria | Spanish | Name of a princess. | F | |
| 293 | Erlene | Spanish | Shield. From the German name Herlinde. | F | |
| 294 | Erlina | Spanish | Shield. From the German name Herlinde. | F | |
| 295 | Ernesta | Spanish | Serious; determined. Feminine of Emest. | F | |
| 296 | Eskama | Spanish | Merciful. | F | |
| 297 | Eskame | Spanish | Merciful. | F | |
| 298 | Esma | Spanish | Emerald. | F | |
| 299 | Esme | Spanish | Emerald. | F | |
| 300 | Esmeralda | Spanish | The emerald gemstone. Famous bearer: the heroine of Victor Hugo's novel 'The Hunchback of Notre Dame'. | F | |